Despite some symptom overlap between PTSD and other disorders, PTSD has several unique features that distinguish it from other disorders. DSM-5 provides specific differential diagnosis guidelines in order to help clinicians assign the most appropriate diagnoses.

The following elements are useful in distinguishing symptoms of PTSD from symptoms of other disorders:

  1. PTSD must be linked to a Criterion A stressor (i.e., a traumatic event), not just a stressful event.
  2. PTSD symptoms must be tied to the traumatic event either through content (e.g., memories of the event) or timing (i.e., they started or got worse after trauma exposure).